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目的通过对肝硬化患者进行视觉诱发电位(VEP)检查及数字连接试验,探讨VEP对亚临床肝性脑病的诊断价值。方法对30例正常人及62例住院的肝硬化患者采用图形VEP(PVEP)检查,记录PVEP P100潜时和振幅,潜时>105 ms为异常,振幅<6μV为异常;数字连接试验超过60 s为异常,同时进行脑电图检查及学氨检测。结果PVEP异常34例(54.84%),数字连接试验异常24例(38.71%),两者均异常21例(33.87%),三组比较差异有统计学意义(χ2=6.03,P<0.01)。结论视觉诱发电位联合数字连接试验对亚临床肝性脑病的诊断有较高的敏感度和特异度,是诊断亚临床肝性脑病的可靠依据。
Objective To investigate the value of VEP in the diagnosis of subclinical hepatic encephalopathy by examining the visual evoked potentials (VEPs) and digital connections in cirrhotic patients. Methods VEP (PVEP) was used to examine PVEP P100 latency and amplitude in 30 normal subjects and 62 inpatients with cirrhosis. The latent period> 105 ms was abnormal and the amplitude was less than 6μV. The digital connection test exceeded 60 s Abnormal, while EEG examination and ammonia test. Results There were 34 cases (54.84%) with PVEP abnormality, 24 cases (38.71%) with abnormal digital connection test and 21 cases (33.87%) with abnormality in both groups. There was significant difference between the three groups (χ2 = 6.03, P <0.01). Conclusions Visual evoked potential combined with digital connectivity test for the diagnosis of subclinical hepatic encephalopathy have a higher sensitivity and specificity, is a reliable basis for the diagnosis of subclinical hepatic encephalopathy.