论文部分内容阅读
目的比较急诊与限期经皮冠脉介入(PCI)术对急性心肌梗死(AMI)后心率变异性(HRV)及心功能的影响。方法共收集随访资料完整的120例AMI患者,包括行急诊PCI治疗42例和行限期PCI治疗38例;而未行任何冠脉再灌注治疗(包括静脉溶栓或PCI术)40例为对照组。分析比较3组患者AMI后1个月、6个月随访时动态心电图检查中的HRV资料及心脏超声检查测定的左室射血分数(LVEF)。结果 AMI后1、6个月时,与未行任何冠脉再灌注治疗的对照组患者相比较,PCI治疗组患者HRV时域指标SDNN、SDANN、r MSSD、PNN50及LVEF均显著提高,而且急诊PCI治疗组患者较限期PCI治疗组患者进一步提高,差异性均有统计学意义(P<0.05,P<0.01)。结论急诊与限期PCI都可以改善提高AMI患者的HRV及心功能,尤以急诊PCI更为显著。
Objective To compare the effects of acute and limited percutaneous coronary intervention (PCI) on heart rate variability (HRV) and cardiac function after acute myocardial infarction (AMI). Methods A total of 120 patients with AMI who were followed up were enrolled, including 42 cases undergoing emergency PCI and 38 cases undergoing PCI. However, 40 cases undergoing coronary reperfusion (including intravenous thrombolysis or PCI) . The HRV data of 1-month and 6-month follow-up were analyzed and compared between the three groups. The left ventricular ejection fraction (LVEF) was measured by echocardiography. Results At 1 month and 6 months after AMI, HRV time domain indices SDNN, SDANN, rMSSD, PNN50 and LVEF were significantly increased in PCI group compared with those in control group without coronary reperfusion Patients in PCI group were further improved than those in PCI group, the difference was statistically significant (P <0.05, P <0.01). Conclusion Both emergency and PCI can improve HRV and cardiac function in patients with AMI, especially in emergency PCI.