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目的:鼻咽癌患者局部病灶化疗方法方案分析。方法:选取宾县人民医院2011年1月-2013年12月收治的60例鼻咽癌患者局部化疗方法进行分析。结果:治疗结束后3个月评价疗效,近期治愈49例,明显好转11例。结论:用化疗手段治疗未分化鼻咽癌已是临床常规治疗方法。大量的Ⅱ期临床研究中,单药有效的有:阿霉素、顺铂、博莱霉素。而长春碱类、MTX和5-FU的疗效一般。抗烷化剂的缓解期比较短。阿霉素的单药效果良好。
Objective: To analyze the chemotherapy of local lesion in patients with nasopharyngeal carcinoma. Methods: Totally 60 cases of nasopharyngeal carcinoma patients treated by Binxian People’s Hospital from January 2011 to December 2013 were selected for local chemotherapy. Results: Three months after the end of treatment, the curative effect was evaluated, 49 cases were cured recently, and 11 cases improved obviously. Conclusion: The treatment of undifferentiated nasopharyngeal carcinoma with chemotherapy is a routine clinical treatment. A large number of phase Ⅱ clinical studies, single-drug effective are: doxorubicin, cisplatin, bleomycin. The vinca alkaloids, MTX and 5-FU general effect. Alkali-resistant agents have a shorter remission period. Adriamycin single effect is good.