本文的目的是研究血管收缩素(serotonin)对正常人鼻粘膜的影响,并与组胺相比较。对象为14名正常人,年龄16～46岁,男女各半,均无特应病史、常年性鼻炎史或慢性呼吸系疾患,2周内无感冒史。试验按双盲法进行。先用磷酸盐缓冲液喷入鼻腔,然后每隔15分钟喷入血管收缩素或组胺。血管收缩素的剂量为120、600及3000μg,组胺的剂量为15、75及375μg。两种药物的试验相隔7天,在同一时间进行。激发后 The purpose of this paper is to investigate the effect of serotonin on normal human nasal mucosa compared to histamine. Subjects for 14 normal people, aged 16 to 46 years old, half male and female, no special history, perennial rhinitis or chronic respiratory disease, no history of cold within 2 weeks. Test by double-blind method. Spray nasally into the nasal cavity with phosphate buffered saline and then inject either angiotensin or histamine every 15 minutes. The doses of angiotensin were 120, 600 and 3000 μg, and the histamine doses were 15, 75 and 375 μg. The two drugs were tested seven days apart at the same time. After excitation