淋巴细胞和巨噬细胞是免疫学最重要的细胞基础。这些细胞激活后,可以产生各自的细胞因子(Cytokine),作为细胞间的信使,扩充反应细胞的数量并调节效应细胞的功能。巨噬细胞产生的淋巴细胞激活因子和淋巴细胞产生的T细胞生长因子是当今免疫学界最活跃的研究课题之一。 Gery等于1972年首先发现淋巴细胞激活因子(Lymphocyte Activating FactorLAF),以后证实是由巨噬细胞产生的。现已建立了产生LAF的细胞系,并得 Lymphocytes and macrophages are the most important cellular bases for immunology. When activated, these cells produce their own cytokines that act as messengers of the intercellular space, expanding the number of reactive cells and regulating effector cell function. Lymphocyte activating factor produced by macrophages and T-cell growth factor produced by lymphocytes are one of the most active research topics in immunology field today. Gery was first discovered in 1972, lymphocyte activation factor (Lymphocyte Activating FactorLAF), later confirmed to be produced by macrophages. LAF-producing cell lines have now been established and obtained