恶性淋巴瘤常伴有发热,进行性淋巴结及脾肿大,但有时临床症状不典型极易造成误诊。本文报道1例如下。朱某某,男,52岁。因持续不规则发热伴右上腹痛5天,于1977年5月1日入院。患者于1976年12月初曾有不规则发热伴黄疸、皮肤搔痒而就诊。发现两腋下淋巴结花生米大小,质中等,有触痛。脾肋下4cm,无腹水征。化验检查总胆红素102.6μmol/L,黄疸指数50U,凡登白试验延迟反应,SGPT及AKP正常。LDH12.53μmol·s~(-1)/L,AFP阴性。因黄疸原因待查于12月6日入传染病院治疗。经治疗发热、黄疸消退,于12月29日出院。出院后又有不规则发热,且伴右上腹痛再次入院。体检:除黄疸已消失外,余同1976年12月门诊所见。肝功能正常,A超示肝较密微小波, Malignant lymphoma is often accompanied by fever, progressive lymph nodes and splenomegaly, but sometimes atypical clinical symptoms can easily lead to misdiagnosis. This article reports 1 case as follows. Zhu Moumou, male, 52 years old. Due to persistent irregular fever with right upper quadrant pain for 5 days, on May 1, 1977 admission. Patients in early December 1976 had irregular fever with jaundice, itchy skin and treatment. Found two axillary lymph nodes peanuts size, medium quality, tenderness. Spleen ribs 4cm, no signs of ascites. Laboratory tests total bilirubin 102.6μmol / L, jaundice index 50U, Vandenbai test delayed response, SGPT and AKP normal. LDH12.53μmol · s -1 / L, AFP negative. Due to the reasons for jaundice to be investigated on December 6 into the infectious disease hospital. After treatment fever, jaundice subsided, was discharged on December 29. Discharged after another irregular fever, and with right upper quadrant abdominal pain again hospitalized. Physical examination: In addition to jaundice has disappeared, more than I found with the clinic in December 1976. Liver function is normal, A ultrasound shows liver more dense micro-wave,