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目的了解河西区出生缺陷的发生率和种类,探讨引起出生缺陷的相关因素。方法对我区2006年10月1日～2008年6月30日出生的7599例围产儿进行监测,监测范围为妊娠满28W～产后7d。结果检出出生缺陷76例,出生缺陷发生率为10‰,顺位依次为:副耳19例,色素痣9例,唇腭裂7例,斑6例,先天愚5例,多指(趾)5例,先天性心脏病4例,外耳畸形4例,脊柱裂3例,肢体短缩3例,腹裂2例,尿道下裂2例,直肠肛门闭锁2例,其他5例。结论出生缺陷的发生与环境、孕期服药、孕妇年龄、孕期合并症、并发症及营养因素等有关。出生缺陷的防治以预防为主,加强产前咨询,并应采用B超、生化等手段进行早期筛查,尽早发现异常,采取措施,降低出生缺陷的发生。
Objective To understand the incidence and types of birth defects in Hexi District and explore the related factors that cause birth defects. Methods 7599 cases of perinatal children born in our district from October 1, 2006 to June 30, 2008 were monitored. The monitoring range was 28W ~ 7 days postpartum. Results 76 cases of birth defects were detected, the incidence of birth defects was 10 ‰. The order of the order was 19 cases of accessory ear, 9 cases of pigmented nevus, 7 cases of cleft lip and palate, 6 cases of spot, 5 cases of idiopathic fool, 5 cases, 4 cases of congenital heart disease, 4 cases of external ear deformities, 3 cases of spina bifida, 3 cases of limb shortening, 2 cases of abdominal fissure, 2 cases of hypospadias, 2 cases of rectal anal atresia, the other 5 cases. Conclusions The occurrence of birth defects is related to the environment, medication during pregnancy, the age of pregnant women, pregnancy complications, complications and nutritional factors. Prevention of birth defects to prevention, strengthen prenatal counseling, and B-ultrasound, biochemical and other means should be used for early screening, early detection of abnormalities, to take measures to reduce the incidence of birth defects.