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急性白血病是对化疗有反应且诱导缓解率较高的恶性肿瘤 ,但对多种化疗药物的耐受是成功治疗的主要障碍之一。白血病细胞耐药的原因很多 ,目前公认的最主要的是多药耐药基因的过度表达。本文就急性白血病多药耐药性的研究现状进行综述。1 多药耐药性的概念所谓耐药性是指白血病
Acute leukemia is a malignant tumor that responds to chemotherapy and has a high induction of remission rate. However, tolerance to various chemotherapeutic drugs is one of the major obstacles to successful treatment. Leukemia cell resistance for many reasons, the most recognized is the most important multi-drug resistance gene overexpression. This article reviews the research status of multi-drug resistance in acute leukemia. The concept of multi-drug resistance The so-called drug resistance refers to leukemia