典型的偏头痛有三组不同症状:局部神经系缺陷、头痛及各种植物神经症状,最常见的是呕吐。这些植物神经症状常在头痛严重前出现,包括恶心、呕吐、情绪改变、渴感、少尿、血管运动不稳定性(眩晕,苍白,出汗)。虽然偏头痛病因不明,但 Hanington 等已提出在疾病早期发生血小板聚集和内源性血小板胺类的释放。这些胺类可以改变血管的渗透性和血管的直径,因而引起头痛和暂时的神经功能障碍。血小板释放的这些胺类主要是5-羟色胺(5HT),但去甲肾上腺素 Typical migraine headaches have three different groups of symptoms: local nervous system defects, headaches, and various autonomic symptoms, most commonly vomiting. These autonomic symptoms often precede severe headaches, including nausea, vomiting, mood changes, thirst, oliguria, and vasomotor instability (dizziness, paleness, sweating). Although the cause of migraine is unknown, Hanington et al. Have proposed platelet aggregation and release of endogenous platelet amines early in the disease. These amines can alter the permeability of blood vessels and the diameter of blood vessels, thus causing headaches and temporary neurological dysfunction. These amines released by platelets are primarily serotonin (5HT), but norepinephrine