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先天性甲状腺功能低下症(CH),简称甲低,是由于先天因素使甲状腺激素分泌减少,最终导致患儿生长障碍,智力落后。由于甲低在新生儿期缺乏特异性的临床症状,很容易被忽略而延误治疗,从而造成患儿不可逆的智力及体格生长发育障碍。如果进行早期诊断和治疗,孩子即能健康成长。它是一种常见的、可以预防的、引起小儿智力及体格发育落后的疾病之一。为此,甲低当前已成为世界各国新生儿疾病筛查的主要项目之一。 1 材料和方法 1.1 筛查对象:1997年9月～1999年9月在河南省18个地市的69家医院出生的新生儿,产后48小时以后采取足跟外侧部位血液1～3滴于美国进口的SS—903新生儿筛查专用滤纸上,室温空气干燥3小时以上,放塑料袋内4℃冰箱保存备测。
Congenital hypothyroidism (CH), referred to as hypothyroidism, is due to congenital factors to reduce thyroid hormone secretion, eventually leading to growth disorders in children, mental retardation. As hypothyroidism in the absence of specific neonatal clinical symptoms, it is easy to be ignored and delay treatment, resulting in irreversible intellectual and physical growth disorders in children. Children develop healthily if diagnosed and treated early. It is one of the common and preventable causes of childhood mental retardation and physical development. To this end, A low now has become one of the world’s major screening of neonatal diseases. 1 Materials and Methods 1.1 Screening: September 1997 ~ September 1999 in Henan Province, 18 cities in 69 hospitals born newborns, 48 hours after the birth to take the heel lateral part of the blood 1 to 3 drops in the United States Import SS-903 neonatal screening filter paper, air-dried at room temperature for more than 3 hours, place the plastic bag 4 ℃ refrigerator for the preparation of the test.