论文部分内容阅读
目的:探讨脓毒性休克患者血乳酸测定的意义和临床价值。方法:选择88例脓毒性休克患者为研究对象,依据临床预后分为存活组68例和死亡组20例。测定两组患者入院时、入院后6、24、48 h血乳酸浓度,观察两组患者血乳酸清除率与APACHEⅡ评分之间的关系。结果:存活组脓毒性休克患者入院时、入院后6、24、48 h动脉血乳酸水平明显低于死亡组(P<0.01);血乳酸清除率明显高于死亡组,APACHEⅡ评分明显低于死亡组(P<0.05、0.01)。结论:动脉血乳酸水平可准备预测患者疾病严重程度及预后,为临床治疗提供参考指导。
Objective: To investigate the significance and clinical value of blood lactate determination in patients with septic shock. Methods: A total of 88 patients with septic shock were selected as study subjects and divided into survival group (n = 68) and death group (n = 20) according to clinical prognosis. The concentrations of blood lactic acid at 6, 24, and 48 h after admission were measured at admission, and the relationship between blood lactic acid clearance and APACHE II scores was observed. Results: The levels of arterial blood lactic acid at 6, 24 and 48 h after admission were significantly lower in survivors than those in death groups (P <0.01). The clearance rate of serum lactic acid was significantly higher than that of death group, and the APACHE Ⅱ score was significantly lower than that of death group Group (P <0.05, 0.01). Conclusion: Arterial lactate levels can be used to predict the severity and prognosis of patients and provide reference for clinical treatment.