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目的：研究并分析少白细胞输液技术在降低输血不良反应中的临床效果。方法：我院2013年5月-2016年5月期间共收治输血患者198例，随机分组，对照组患者运用常规输血方法，观察组患者运用少白细胞输液技术进行输血，对比两组患者不良反应发生情况。结果：对照组患者发热5例，过敏5例，蛋白尿4例，输血不良反应发生率为14.14%，观察组患者发热2例，过敏1例，蛋白尿1例，输血不良反应发生率为4.04%，两组对比，差异具有显著性（P<0.05）。结论：运用少白细胞输液技术为患者进行输血治疗可降低患者输血不良反应发生率，极为安全、有效，值得推广。“,”objective: to study and analyze the leukocyte infusion technology in reducing blood transfusion adverse reactions in clinical effect. Methods: from May 2013 to May 2016 treated patients, 198 cases of blood transfusion, randomized, control group patients using conventional blood transfusion method, observation group of patients with less leukocyte infusion technology for blood transfusion, compared two groups of patients with adverse reactions occur. Results: control group in patients with fever in 5 cases, al ergies in 5 cases, 4 cases were proteinuria, blood transfusion the incidence of adverse reactions was 14.14%, the observation group of patients with fever in 2 cases, al ergies in 1 case, proteinuria in 1 case, blood transfusion the incidence of adverse reactions was 4.04%, compared the two groups, with significant difference (P < 0.05). Conclusion: using less leukocyte infusion technology for patients with blood transfusion therapy can decrease the incidence of patients with blood transfusion reactions, is very safe, effective, worthy of promotion.