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目的探讨飞行员冠心病的危险因素与冠状动脉病变严重程度之间的关系。方法研究对象为2002—2011年在中国民用航空局民用航空医学中心进行健康检查鉴定的飞行员40人。均为男性,年龄在38～60岁,均行冠状动脉造影(CAG)检查,30人确诊为冠心病,10人确诊为冠状动脉粥样硬化症。结果①将40名飞行员分为冠心病组和冠状动脉粥样硬化组。冠脉硬化组较冠心病组年轻(P<0.05),体重指数(BMI)冠脉硬化组和冠心病组均>24,收缩压、舒张压、低密度脂蛋白脂固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、甘油三酯(TG)、空腹血糖以及危险因素数目在两组间无统计学差异。②30名冠心病飞行员按照冠状动脉病变支数分为1支病变组(17人),2支病变组(9人)和3支病变组(4人),LDL-C水平在3支病变组明显升高(P<0.05),BMI、收缩压、舒张压、HDL-C、TG、空腹血糖以及危险因素数目在3组间差异无统计学意义。结论飞行员冠心病严重程度与年龄、BMI、LDL-C有关,与危险因素数目无关。
Objective To investigate the relationship between the risk factors of coronary heart disease and the severity of coronary artery disease in pilots. Methods The study population consisted of 40 pilots who were certified by the Civil Aviation Medical Center of Civil Aviation Administration of China from 2002 to 2011. All men, aged 38 to 60 years old, underwent coronary angiography (CAG) examination, 30 were diagnosed as coronary heart disease, 10 were diagnosed with coronary atherosclerosis. Results ①All pilots were divided into coronary heart disease group and coronary atherosclerosis group. Coronary artery disease group was younger than coronary heart disease group (P <0.05), body mass index (BMI) coronary heart disease group and coronary heart disease group were> 24 systolic blood pressure, diastolic blood pressure, low density lipoprotein cholesterol , HDL-C, triglyceride (TG), fasting blood glucose and the number of risk factors were not statistically different between the two groups. ②30 coronary heart disease pilots were divided into 1 diseased group (17 patients), 2 diseased group (9 patients) and 3 diseased group (4 patients) according to the number of coronary lesion. The level of LDL-C in 3 diseased group was significantly (P <0.05). There was no significant difference in BMI, systolic blood pressure, diastolic blood pressure, HDL-C, TG, fasting blood glucose and the number of risk factors among the three groups. Conclusion The severity of coronary heart disease in pilots is related to age, BMI and LDL-C, but not to the number of risk factors.