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为探讨尿胰蛋白酶原-2在急性胰腺炎早期诊断中的应用价值及与其它方法的比较,对28例急性胰腺炎病人和76例非急性胰腺炎急腹症病人,急诊检测尿胰蛋白酶原-2及尿淀粉酶,结合临床检查后再测血淀粉酶和脂肪酶以确诊或排除急性胰腺炎。结果表明,尿胰蛋白酶原-2试带法特异性为95%,灵敏度为93%;血淀粉酶定量分析高、低截断值时特异性分别为97%、91%,灵敏度分别为70%、85%;尿淀粉酶定量分析高、低截断值时特异性分别为97%、88%,灵敏度分别为51%、83%;脂肪酶特异性为93%,灵敏度为89%。结论:尿胰蛋白酶原-2试带法灵敏度高,作为急性胰腺炎病人尿液筛查有很大可靠性。
In order to investigate the value of urinary trypsinogen-2 in the early diagnosis of acute pancreatitis and compare with other methods, 28 patients with acute pancreatitis and 76 patients with acute pancreatitis without acute abdomen, emergency detection of urinary trypsinogen -2 and urinary amylase, combined with clinical tests and then measured serum amylase and lipase to confirm or exclude acute pancreatitis. The results showed that the specificity of urinary trypsinogen-2 test was 95% and the sensitivity was 93%. The specificity of serum amylase was 97%, 91%, and the sensitivity was 70% 85%. The specificity of urinary amylase for quantitative analysis of high and low cutoff values was 97% and 88%, respectively, and the sensitivity was 51% and 83% respectively. The specificity of lipase was 93% and the sensitivity was 89%. Conclusion: Urine trypsin-2 test strip method with high sensitivity, as the screening of urine in patients with acute pancreatitis have great reliability.