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目的：观察强噪声对听觉脑干慢波电位波幅的即时性增大效应。方法：将３６只豚鼠分３组，分别暴露在９５、１１５、１２５ｄＢＳＰＬ不同声强的噪声中，３０ｍｉｎ后，立即检测听觉脑干慢波电位（ＳＷ－ＢＡＥＰ）正相波的波幅。结果：在９５ｄＢＳＰＬ组，可见１ｋＨｚ短纯音诱发的ＳＷ－ＢＡＥＰ波幅明显增大（Ｐ＜０．０５），在１１５ｄＢＳＰＬ组，增大更加明显（Ｐ＜０．０１）；在１２５ｄＢＳＰＬ组，短声及１、４ｋＨｚ短纯音诱发的ＳＷ－ＢＡＥＰ波幅均有减小趋势，但只４ｋＨｚ差异显著（Ｐ＜０．０５）。结论：表明只有在适当强度的噪声暴露后，才能引起ＳＷ－ＢＡＥＰ正相波的波幅即时性增大，并具有频率特性；即时性增大效应的出现，常预示出现暂时性阈移（ＴＴＳ），因而可用于永久性阈移（ＰＴＳ）的早期预测。
Objective: To observe the effect of strong noise on the instantaneous increase of auditory brainstem slow wave potential amplitude. Methods: Thirty-six guinea pigs were divided into three groups and exposed to noise with different intensities of 95, 115 and 125 dBSPL respectively. After 30 minutes, the amplitudes of normal-wave of auditory brainstem slow wave potential (SW-BAEP) were detected. Results: In the 95 dB SPL group, the amplitude of SW-BAEP induced by 1 kHz short pure tone was significantly increased (P <0.05), and the amplitude was significantly increased in the 115 dB SPL group (P <0.01). In the 125 dB SPL group, The amplitudes of SW-BAEP induced by 1 and 4 kHz short pure tones all decreased, but the difference was only significant at 4 kHz (P <0.05). CONCLUSIONS: It is shown that the instantaneous amplitude of the normal phase of SW-BAEP can be increased and the frequency characteristics of the SW-BAEP can only be caused by the exposure of the appropriate intensity of noise. The appearance of the temporal increase effect often indicates the temporary threshold shift (TTS) , Which can be used for the early prediction of permanent threshold shift (PTS).