论文部分内容阅读
亚油酸是食物中最重要的前列腺素前体,在先前试验中,作者发现在健康男性,饮食中适量亚油酸摄入能大大增加胃粘膜前列腺素E分泌,抑制胃酸排出量。本研究旨在探索十二指肠溃疡患者饮食中亚油酸相对缺乏与溃疡形成的关系。方法:研究对象为35名男性,年龄21～79岁(平均45岁),经内镜检查均证实为慢性十二指肠溃疡,无消化性溃疡手术史,未服用类固醇抗炎药、组织胺受体拮抗药或前列腺素类似药物;另有年龄、社会阶层,吸烟史相同的35名健康男性为对照组。局麻下,用直径
Linoleic acid is the most important prostaglandin precursor in food. In previous experiments, the authors found that adequate intake of linoleic acid in the diet significantly increased gastric mucosal prostaglandin E secretion and inhibited gastric acid output in healthy men. The aim of this study was to explore the relationship between the relative lack of linoleic acid and the formation of ulcers in the diet of patients with duodenal ulcer. METHODS: The study population was 35 males and aged 21 to 79 years (mean, 45 years). Chronic duodenal ulcers were confirmed by endoscopy. No history of peptic ulcer surgery, no administration of steroid anti-inflammatory drugs, histamine Receptor antagonist or prostaglandin similar drugs; otherwise age, social class, smoking history of the same 35 healthy men as the control group. Under local anesthesia, with diameter