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７６例发病≤６ｈ的急性心肌梗塞（ＡＭＩ）患者随机分为两组，根据常规心电图初始ＳＴ段的抬高预计和最后ＱＲＳ改变估计心肌梗塞范围（ＭＩＳ），观察尿激酶对ＭＩＳ的影响。结果表明：ＭＩＳ在对照组治疗前后差异无显著性意义（Ｐ＞０．０５）；在尿激酶组治疗前后差异有显著性意义（Ｐ＜０．０１）；两组ＭＩＳ变化百分比差异有显著性意义（Ｐ＜０．０１）。其中尿激酶组未通亚组治疗前后ＭＩＳ差异无显著性意义（Ｐ＞０．０５），再通亚组治疗前后ＭＩＳ差异有显著性意义（Ｐ＜０．０１）。在两组未通病例中ＭＩＳ变化百分比差异有显著性意义（Ｐ＜０．０５）。提示尿激酶溶栓治疗可显著减少ＭＩＳ。挽救缺血濒死的心肌，这一效果在冠状动脉（冠脉）再通的病例中尤为突出，对冠脉未通病例也有一定作用。
Sixty-six patients with acute myocardial infarction (AMI) ≤6h were randomly divided into two groups. The extent of myocardial infarction (MIS) was estimated according to the initial ST elevation and the last QRS changes of conventional electrocardiogram to observe the effect of urokinase on MIS. The results showed that MIS had no significant difference before and after treatment in the control group (P> 0.05), and there was significant difference in the urokinase before and after treatment (P <0.01). There was significant difference in MIS percentage between the two groups Significance (P <0.01). There was no significant difference between the two groups (P> 0.05), but there was no significant difference between the two groups (P> 0.05). There was a significant difference in the percent change of MIS between the two groups of unacceptable cases (P <0.05). Prompt urokinase thrombolytic therapy can significantly reduce MIS. Saving ischemic dying myocardium, this effect is particularly prominent in the case of recanalization of the coronary artery (coronary artery), but also has a role on coronary artery failure cases.