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[目的]了解武汉大学中南医院1995～2009年间妇科恶性肿瘤住院患者的构成特点及变化趋势。[方法]对武汉大学中南医院2751例妇科恶性肿瘤住院患者的临床及病理资料进行回顾性分析。[结果]①各类妇科恶性肿瘤住院人数呈上升趋势,构成比前4位依次为宫颈癌、卵巢恶性肿瘤、子宫内膜癌和恶性滋养细胞肿瘤。其中宫颈癌患者比例呈上升趋势(P=0.001);卵巢恶性肿瘤、子宫内膜癌和恶性滋养细胞肿瘤比例呈下降趋势(P=0.014,P=0.009,P=0.001)。②宫颈癌发病年轻化,35岁以下宫颈癌患者增加。③各类妇科恶性肿瘤地域分布无变化,宫颈癌患者主要集中于农村地区,卵巢恶性肿瘤、子宫内膜癌、外阴阴道恶性肿瘤、子宫肉瘤患者大多集中于城镇。④妇科恶性肿瘤患者就诊时大多处于早期(Ⅰ、Ⅱ期),但卵巢恶性肿瘤患者多为中晚期(Ⅲ、Ⅳ期)。⑤各类妇科恶性肿瘤的病理组织学类型分布各时期无统计学差异。[结论]妇科恶性肿瘤住院患者人数呈持续增加趋势,且住院患者以早期为主。
[Objective] To understand the characteristics and trends of inpatients with gynecologic malignancies in Central South Hospital of Wuhan University from 1995 to 2009. [Methods] The clinical and pathological data of 2751 inpatients with gynecological malignant tumors in Zhongnan Hospital of Wuhan University were retrospectively analyzed. [Results] ①The number of hospitalizations of various types of gynecological malignancies showed an upward trend, which was followed by cervical cancer, ovarian cancer, endometrial cancer and malignant trophoblastic tumor. The proportion of patients with cervical cancer showed an upward trend (P = 0.001). The proportion of ovarian cancer, endometrial cancer and malignant trophoblastic tumor showed a decreasing trend (P = 0.014, P = 0.009, P = 0.001). ② young cervical cancer, cervical cancer patients under 35 years of age increased. ③ There was no change in the geographical distribution of various types of gynecological malignancies. The patients with cervical cancer mainly concentrated in rural areas. Most of the patients with ovarian cancer, endometrial cancer, vulvovaginal malignancies and uterine sarcomas were concentrated in the cities and towns. Most gynecologic malignancies are in the early stages of treatment (stage I and stage II), but most of the ovarian cancer patients are in the advanced stages (stages III and IV). ⑤ various types of gynecological malignant tumor pathological histological distribution of each period no significant difference. [Conclusion] The number of inpatients with gynecological malignancies continues to increase, and the number of hospitalized patients is mainly early stage.