为了估计输血后肝炎的发生率以及查明影响输血后肝炎发生的因素,作者对1974～1979年间在美国不同地区四个医疗中心中接受输血的1,513例患者进行了一项前瞻性的随访研究。1,513例患者的年龄在16岁以上,输血前9个月内未接受过输血,输血前6个月内无肝炎接触史,患者本身无病毒性肝炎或其它肝病史。作者在输血前后对每例患者作血清丙氨酸转氨酶(简称ALT)测定,并检测甲 To estimate the incidence of post-transfusion hepatitis and to identify the factors that influence post-transfusion hepatitis, we conducted a prospective follow-up study of 1,513 patients who transfused blood from four centers in different parts of the United States between 1974 and 1979. 1,513 patients were over 16 years old and had not received blood transfusion within 9 months prior to transfusions, no history of hepatitis exposure within 6 months prior to transfusion, and no history of viral hepatitis or other liver disease in patients themselves. The authors before and after transfusion for each patient serum alanine aminotransferase (referred to as ALT) determination and detection of a