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在我国,肝炎后肝硬化导致的门静脉高压较为常见,目前药物治疗门静脉高压,主要通过降低肝内压力、减少门静脉血流量来实现治疗目的。目前都有哪些常用的降低门脉压力的药呢?我们一起来看一下吧。(1)普萘洛尔其是目前降低门静脉压力、预防静脉曲张出血的主要药物,对β1受体阻断作用较强,可使心率减慢,心排血量减少,从而降低血压,同时反射性引起外周阻力增加,使肝肾器官血流减少,降低门静脉压力。普萘洛尔同时可阻断β2受体,收缩支气管平滑肌,故支气管
In our country, portal hypertension caused by posthepatitic cirrhosis is more common. At present, the drug treatment of portal hypertension mainly aims to reduce the intrahepatic pressure and reduce the portal vein blood flow to achieve the therapeutic goal. What are the commonly used drugs for lowering portal pressure now? Let’s take a look. (1) Propranolol is currently the main drug for reducing portal vein pressure and preventing variceal bleeding, and has a strong blocking effect on β1 receptor, which can slow the heart rate and reduce cardiac output, thereby reducing blood pressure and reflex Caused by increased peripheral resistance, blood flow to the liver and kidney to reduce portal pressure. Propranolol can also block β2 receptors, bronchial smooth muscle contraction, so the bronchus