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结扎输精管后,有少数会出现结节、附睾管内精子淤积和肉芽肿等合并症。近年来用乳倍膏治疗痛性结节337例,有效率达98.4～99.2%,为探讨乳倍膏治疗作用机制,我们进行了实验研究。材料与方法实验用170～190g雄性大白鼠作集束输精管结扎。术后15天用乳倍膏外敷阴囊皮肤(乳倍膏的组成为乳香、五倍子、没药、大黄……等)。用药时间分别为10天(对照组3只,药物组4只),15天(对照组18只,药物组17只)。用药后杀死动物,取“结节”以及部分动物睾丸、附睾,用10%福尔马林固定,石腊切片,H·E染色,部分切片作革兰氏阴、阳性细菌染色。
After ligation of the vas deferens, complications such as nodules, spermatophoresis in the epididymal duct, and granulomas occur in a few cases. In recent years, 337 cases of painful nodules were treated with breast cream, and the effective rate was 98.4 to 99.2%. We conducted an experimental study to investigate the therapeutic mechanism of breast cream. Materials and Methods Experiments Male Wistar rats (170-190 g) were used for bundle vasectomy. 15 days after the use of milk cream external scrotal skin (milk cream composition of frankincense, gall, myrrh, rhubarb ... ... etc.). The time of treatment was 10 days (3 in the control group and 4 in the drug group) and 15 days (18 in the control group and 17 in the drug group). After the animals were sacrificed, the animals were sacrificed, and the “nodules” and parts of the animals’ testes and epididymides were fixed with 10% formalin, paraffin sections, H.E staining, and some sections were stained for gram negative and positive bacteria.