论文部分内容阅读
目的为了解食管癌切除胃食管吻合术后近期内患者发生胃食管返流的情况。方法对１０例正常人和３０例患者术后１～３月间进行了残留食管腔内连续２４小时ｐＨ监测。结果发现所有患者的ｐＨ总得分、２４小时返流次数、大于５分钟的返流次数、最长返流时间和ｐＨ＜４的总时间均明显高于正常人（Ｐ＜０．０１）。同时发现有明确胸骨后烧灼感、反酸、胸痛等胃食管返流症状者仅１１例，占总监测患者的３６．７％。结论所有胃食管吻合术后患者近期内均存在胃食管返流症，且多以无症状返流形式存在。对术后发生胃食管返流症的原因进行了分析并提出了相应的预防治疗措施。
Objective To understand the occurrence of gastroesophageal reflux in patients with gastroesophageal anastomosis after esophagectomy. Methods Continuous 24-hour pH monitoring of residual esophageal cavity was performed in 10 normal subjects and 30 patients between January and March. The results showed that the total pH of the patients, the number of regurgitation in 24 hours, the number of regurgitation more than 5 minutes, the longest reflux time, and the total time of pH<4 were significantly higher than those in normal subjects (P<0.01). At the same time, it was found that there were only 11 cases of gastroesophageal reflux symptoms such as poststernal burning sensation, acid reflux, and chest pain, which accounted for 36.7% of the total monitored patients. Conclusions Gastroesophageal reflux disease is present in all patients after gastroesophageal anastomosis in the near future, and most of them present in the form of asymptomatic regurgitation. The causes of postoperative gastroesophageal reflux disease were analyzed and corresponding preventive and therapeutic measures were proposed.