我院自1981～1989年共收治急性有机磷中毒者337例,其中磷中毒性脊髓病9例(3.2%),并经4～8年随访,现报告如下。临床资料一、多见于青壮年、女性。本组9例,女性6例(67%),年龄21～43(平均25.6)岁。二、潜伏期:6小时～21天,急性起病,多在劳动时或劳动后发现,平均15.3天。三、临床表现:1.首发症状多为肢端尤以下肢膝关节以下感觉异常,如麻木、蚁感、肌肉疼痛和无力,随之出现肌萎缩。2.突出表现为运动障碍(100%),特征是四肢远端对称性瘫痪(100%)。其趾、指力均为0～Ⅰ°,双手和双足下垂。本组痉挛性瘫痪7例,表现为腱反射亢进、肌痉挛、鸭形步态,不能独自行走。弛缓性瘫痪2例表现为腱反射消失,拖曳步态,不能独自 337 cases of acute organophosphate poisoning were treated in our hospital from 1981 to 1989, including 9 cases of phosphorus-poisoning myelopathy (3.2%), and after 4 to 8 years of follow-up, are as follows. A clinical data, more common in young adults, women. The group of 9 patients, 6 females (67%), aged 21 to 43 (average 25.6) years old. Second, the incubation period: 6 hours to 21 days, acute onset, mostly in labor or labor after the discovery, an average of 15.3 days. Third, the clinical manifestations: 1. The first symptom of the limbs, especially the lower extremity knee particularly sensory abnormalities such as numbness, ants sense, muscle pain and weakness, followed by muscle atrophy. 2. Outstanding performance of dyskinesia (100%), characterized by distal symmetry limb paralysis (100%). The toe, finger force are 0 ~ Ⅰ °, hands and feet drooping. This group of spastic paralysis in 7 cases, manifested as tendon hyperreflexia, muscle spasms, duck-shaped gait, can not walk alone. Flaccid paralysis manifested in 2 cases of tendon reflex disappeared, drag the gait, can not be alone