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目的：探讨四种常用平喘方案对哮喘患者肺功能影响的差异。方法：２３例发作期哮喘患者按随机、交叉方式分别吸入特布他林、溴化异丙托品、两药联合吸入及静脉注射氨茶碱，并测定用药前、用药后１５、３０、６０ｍｉｎ的第１秒用力肺活量（ＦＥＶ１）及峰值流速（ＰＥＦＲ）。结果：四组方案使用后ＦＥＶ１、ＰＥＦＲ均较用药前明显增加，联合用药组增加最明显，氨茶碱组最低，特布他林组与异丙托品组间无差异。结论：联合吸入特布他林、异丙托品是发作期哮喘最有效的平喘方案。
Objective: To investigate the differences of the effects of four commonly used asthma regimens on pulmonary function in asthmatic patients. Methods: Twenty-three patients with asthma attacking were randomly assigned to terbutaline and ipratropium bromide. The two drugs were inhaled and intravenous aminophylline. The levels of aminophylline, 1 second forced vital capacity (FEV1) and peak flow velocity (PEFR). Results: The FEV1 and PEFR of the four groups were significantly increased after treatment compared with before treatment, the combination group was the most obvious increase, aminophylline group the lowest, there was no difference between terbutaline group and ipratropium group. CONCLUSION: Combined inhalation of terbutaline and ipratropium is the most effective antiasthmatic treatment for asthma in the attack phase.