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目的:探讨醋酸加碘染色肉眼观察法(VIA-VILI)筛查宫颈癌的影响因素。方法:对2003例自愿参加宫颈癌筛查的妇女进行问卷调查,采用VIA-VILI方法筛查宫颈癌,并应用病理诊断对筛查结果进行确认,分析可能影响VIA-VILI方法筛查结果的因素。结果:有经验医师对VIA-VILI方法的筛查结果产生有利影响(β<0,OR<1,P<0.05);近3年未参加筛查及患有宫颈炎症对筛查结果产生不利影响(β>0,OR>1,P<0.05);而妊娠次数、分娩方式、生产次数、醋酸作用时间及是否放置IUD等因素对筛查结果影响不明显(P>0.05)。结论:使用VIA-VILI方法进行宫颈癌筛查时,对患有宫颈炎症的妇女要注意减少漏诊,注意降低假阳性率;加强对医师的技术培训;鼓励妇女定期参加宫颈癌筛查;而对于绝经后妇女则不推荐使用VIA-VILI方法筛查宫颈癌。
Objective: To investigate the influencing factors of screening cervical cancer by VIA-VILI. Methods: A total of 2003 women who volunteered for cervical cancer screening were surveyed. The VIA-VILI method was used to screen for cervical cancer. The pathological diagnosis was used to confirm the screening results. Factors that could affect the screening results of VIA-VILI method were analyzed . RESULTS: Experienced physicians had a favorable effect on screening results of the VIA-VILI method (β <0, OR <1, P <0.05); screening results and cervical inflammation in the last 3 years had adverse effects on screening results (β> 0, OR> 1, P <0.05). However, the number of pregnancy, mode of delivery, number of times of production, duration of acetic acid treatment and placement of IUD had no significant effect on screening results (P> 0.05). Conclusions: When using VIA-VILI for cervical cancer screening, women with cervical inflammation should pay attention to reduce missed diagnosis, pay attention to reducing the false positive rate; to strengthen the technical training of doctors; to encourage women to regularly participate in cervical cancer screening; Postmenopausal women do not recommend VIA-VILI for cervical cancer screening.