凋亡是细胞在基因调控下程序性地发生的主动细胞死 ,它与细胞的增殖、分化密切相关 ,在生命延续中发挥不可替代的作用。 1 972年Kerr等提出了这一描述细胞死的概念。进入 90年代以来 ,凋亡相关的研究飞速进展 ,已发现多种与凋亡过程有关的许多分子 ,并逐步阐明了“不同诱因、不 Apoptosis is programmed cell death under the gene regulation. It is closely related to cell proliferation and differentiation, and plays an irreplaceable role in the continuation of life. Kerr et al. Proposed the concept of cell death in 1972. Since the 1990s, there have been rapid advances in apoptosis-related research. A number of molecules related to the apoptotic process have been discovered and have been gradually elucidated as "different triggers, not