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男用节育药棉酚为我国首先发现。对服药者本人的染色体畸变及SCE频率国内已有研究报告,但棉酚对子代的遗传效应,国内外尚无报道。目前公认SCE频率是检测药物活力的比较敏感的指标。为此,我们对15例服用棉酚者复育后所生子女15人(男9人,女6人),年龄3—7
Male birth control gossypol was first discovered in China. There are reports of chromosomal aberrations and SCE frequency in our country. However, the genetic effects of gossypol on offspring have not been reported at home and abroad. SCE frequency is currently recognized as a more sensitive indicator of drug activity. To this end, 15 of 15 children (9 males and 6 females) born after resuscitation after taking gossypol, aged 3-7