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本文报告一例多腺性自身免疫性内分泌病患儿继肾上腺皮质球状带衰竭后发生进行性肾上腺功能衰竭的临床病程。 患儿在(15)/2岁时确诊为甲状旁腺机能减退症,同时伴发皮肤粘膜念珠菌病。当时除测得血钙4.7mg％和血磷7.6mg％外,其他电解质水平均正常,身高为123.4厘米,体重23.7公斤,骨龄为(69)/(12)～(82)/(12)岁,其糖皮质激素和盐皮质激素的基础值和ACTH刺激后的水平均正常。第二年开始用维生素D和钙剂治疗。(23)/2岁时再次测定其糖皮质醇和盐皮质激素的基础值和ACTH刺激后的水平仍无异常发现。
This article reports the clinical course of a case of progressive adrenal failure in children with polyglandial autoimmune endocrine disease following failure of the adrenal cortex. Children (15) / 2 years old diagnosed with hypoparathyroidism, accompanied by skin mucosal candidiasis. At that time, except the blood calcium 4.7mg% and phosphorus 7.6mg%, the other electrolyte levels were normal, height 123.4 cm, weight 23.7 kg, bone age (69) / (12) ~ (82) / (12) , The glucocorticoid and mineralocorticoid and ACTH-stimulated baseline values were normal. The following year began treatment with vitamin D and calcium. (23) / 2 years old again determined the basic values of glucocorticoid and mineralocorticoid and ACTH-stimulated level still no abnormal findings.