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本文报道了ANAE在正常血细胞和白血病细胞的分布,探讨了ANAE在白血病形态分型和免疫分型中的意义;认为:ANA E在血细胞分化成熟过程中出现顺序不同。单核细胞从原始到成熟阶段各期细胞均为阳性,以幼单反应最强。粒系统,ANAE的出现早于过氧化酶,以早幼粒最强,成熟粒细胞减少以至消失。淋巴系统,在T细胞分化成熟过程中,ANAE在后胸腺细胞出现,至成熟T细胞最强,是成熟T细胞的可靠标志。在B细胞分化成熟过程中变化有待观察。ANAE可作为T—CLL的指标。在形态分型中,对M_1和L_1,M_3和M_5的鉴别有一定的卷义。在急淋的免疫分型中,有助于将FALL进一步分为不同的亚型。
This article reports the distribution of ANAE in normal blood cells and leukemia cells, and explores the significance of ANAE in leukemia morphology typing and immunophenotyping. It is concluded that the sequence of ANAE appears during the differentiation and maturation of blood cells. Monocytes from each stage of the original to mature stage cells were positive, with the strongest single response. Granulocyte system, ANAE appeared earlier than peroxidase, with the strongest promyelocytic, mature granulocytes decreased and even disappeared. Lymphatic system, T cell differentiation in the maturation process, ANAE appears in the posterior thymocyte, to mature strongest T cells, is a reliable marker of mature T cells. Changes in the maturation of B cells need to be observed. ANAE can be used as an indicator of T-CLL. In morphological typing, the identification of M_1 and L_1, M_3 and M_5 has some implications. In acute lymphotyping, it helps to further classify FALLs into different subtypes.