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我科应用腹膜透析配合WS-健肾频谱仪及药物治疗重症狼疮性肾炎(LN)3例,疗效满意,报道如下。 例1,女,43岁,因反复低热、关节酸痛、面部红斑、浮肿7月伴少尿,大量腹水2月入院。Hb50g/L,尿蛋白6.1g/24h,A/G=18/27,BUN37.3mmol/L,Scr339.7umol/L,ANA1:640,C_3<2.3mg/L,C_4<1.1mg/L,抗dsDNA抗体阳性。肾活检病理诊断:WHOⅣ型。LN活动指数(AI)8分,慢性指数(CI)4分。经甲基强的松龙1g静滴3天,环磷酰胺(CTX)0.6静滴每月一次,尿激酶2万U加肝素50mg静滴2周,强的松、雷公藤维持治疗。WS-健肾频谱仪(病人坐
In our department, 3 cases of severe lupus nephritis (LN) were treated with peritoneal dialysis and WS-JNR, and the results were satisfactory. The results are reported as follows. Example 1, female, 43 years old, due to repeated fever, joint pain, facial erythema, edema in July with oliguria, a large number of ascites admitted in February. Hb50g / L, urinary protein 6.1g / 24h, A / G = 18/27, BUN37.3mmol / L, Scr339.7umol / L, ANA1: 640, C_3 <2.3mg / dsDNA antibody positive. Renal biopsy pathological diagnosis: WHO Ⅳ type. LN activity index (AI) 8 points, chronic index (CI) 4 points. Methylprednisolone 1g intravenous infusion of 3 days, cyclophosphamide (CTX) 0.6 intravenous infusion monthly urokinase 20,000 U heparin 50mg intravenous infusion of 2 weeks, prednisone, Tripterygium maintenance therapy. WS-kidney spectrum analyzer (patient sitting