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目的探讨宫外孕应用米非司酮联合甲氨蝶呤药物保守治疗的疗效。方法选择2015年8月至2016年8月期间我院接收的90例宫外孕患者为研究对象,按照随机抽签法分为观察组(n=45)和对照组(n=45),对照组应用甲氨蝶呤治疗,观察组应用米非司酮联合甲氨蝶呤保守治疗,比较两组患者的临床疗效。结果两组患者治疗后观察指标情况比较,观察组阴道止血时间、腹痛消失时间、包块消失时间、血β-h CG水平均明显短于对照组(P<0.05);两组患者临床疗效比较,观察组总有效例数明显高于对照组(P<0.05);两组患者不良反应发生情况比较,观察组总发生例数明显低于对照组(P<0.05)。结论宫外孕患者应用米非司酮联合甲氨蝶呤药物保守治疗,能取得十分满意的临床疗效,不仅能缩短患者临床症状消失时间,也能提高患者的生活质量,建议推广。
Objective To investigate the curative effect of conservative treatment with mifepristone combined with methotrexate in ectopic pregnancy. Methods Ninety cases of ectopic pregnancy received in our hospital from August 2015 to August 2016 were selected as observation group (n = 45) and control group (n = 45) Methotrexate treatment, the observation group with mifepristone combined with methotrexate conservative treatment, the clinical efficacy of two groups were compared. Results Compared with the control group, the vaginal bleeding time, disappearance of abdominal pain, disappearance of mass and blood β-h CG level in the two groups were significantly shorter than those in the control group (P <0.05). The clinical effects of the two groups were compared , And the total effective cases in the observation group were significantly higher than those in the control group (P <0.05). The incidence of adverse reactions in the two groups was significantly lower than that in the control group (P <0.05). Conclusion Ectopic pregnancy patients with mifepristone combined with methotrexate conservative treatment can be very satisfied with the clinical efficacy, not only can reduce the disappearance of clinical symptoms, but also improve the quality of life of patients, it is recommended to promote.