过敏性支气管哮喘虽在病生理、免疫药理及免疫疗法等方面取得不少进展,但抗体的作用机制尚未完全解决。 在速发型变态反应中,常可表现为IgE升高,免疫疗法后可测出IgG阻抑抗体增强。而抗体如何反应亦不很清楚。 本报告通过RAST干扰试验发现,临床症状的改善与IgG阻抑抗体的强化及IgE过敏抗体的下降相关联。这或可有助于对患者治疗措施的改善。 Allergic bronchial asthma has made a lot of progress in disease physiology, immunopharmacology and immunotherapy, but the mechanism of action of the antibody has not yet been completely solved. In the rapid onset of allergic reactions, often manifested as elevated IgE, immunosuppressive IgG antibody can be measured after the increase. How antibodies react is not very clear either. The RAST interference test reported in this report found that improvement in clinical symptoms was associated with enhanced IgG suppressor antibodies and decreased IgE allergic antibodies. This may help to improve the patient’s treatment.