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报道105例朝鲜族HBsAg阳性者HDV混合感染情况。HDAg及抗-HD抗体的检测均用Elisa法。105例血清HDAg阳性者为11例,抗-HD抗体阳性者1例,总混合感染率为11`42％.各型乙型肝炎中HDV混合感染率为急性肝炎8.57％,慢性迁延性肝炎12.50％,慢性活动性肝炎19.01％,肝硬化20.20％,HBsAg慢性携带者4％。慢性活动性肝炎,肝硬化的混合感染率显著高于HBsAg慢性携带者及急性肝炎。混合感染时HBeAg阳性率(66.67％)高于HBV单独感染者。这说明HDV和HBV可同时复制,可能有有互相促进作用。
Reported 105 cases of Korean HBsAg-positive HDV mixed infection. Detection of HDAg and anti-HD antibodies using Elisa method. The serum HDAg positive in 105 cases was 11 cases and the anti-HD antibody was positive in 1 case, the total mixed infection rate was 11% ~ 42% .The mixed infection rate of HDV in each type of hepatitis B was 8.57% for acute hepatitis and 12.50 for chronic persistent hepatitis %, Chronic active hepatitis 19.01%, liver cirrhosis 20.20%, chronic HBsAg carriers 4%. Chronic active hepatitis, cirrhosis of the mixed infection rate was significantly higher than chronic carriers of HBsAg and acute hepatitis. The positive rate of HBeAg (66.67%) in mixed infection was higher than that in HBV alone. This shows that HDV and HBV can be copied at the same time, may have mutual promotion.