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目的分析老年男性2型糖尿病骨密度(BMD)变化与空腹血糖(FPG)和糖化血红蛋白(HbAlc)的关系。方法用美国GE Lunar公司生产的Prodigy型双能X线吸收仪(Dual-energy X-ray Absorptiometry,DXA),测定60例70岁以上2型糖尿病(diabetes mellitus T2 DM)患者正位腰椎(L1-L4)骨密度及左侧股骨颈部骨密度,同时检测FPG和HbAlc,并以相同的测量方法对60例70岁以上血糖正常老年男性作配对为对照组,对二部位BMD值、FPG和HbAlc进行回顾性统计分析。结果 2型糖尿病组与非糖尿病组(对照组)腰椎BMD比较无统计学意义(P>0.05),而股骨颈部BMD、FPG和HbAlc比较均有显著性差异(P<0.01)。结论 FPG和HbAlc值越高其股骨颈部BMD值越低。患者代谢控制不良会造成骨量丢失加速,易发骨质疏松。
Objective To analyze the relationship between changes of bone mineral density (BMD) and fasting blood glucose (FPG) and glycosylated hemoglobin (HbAlc) in elderly men with type 2 diabetes mellitus. Methods Sixty patients with diabetes mellitus T2DM over 60 years of age were measured with the Prodigy Dual-energy X-ray Absorptiometry (DXA) manufactured by GE Lunar Co., L4) BMD and left femur neck BMD. Meanwhile, FPG and HbA1c were detected at the same time. The same test method was used to compare 60 BMD elderly people over 70 years of age as control group. BMD value, FPG and HbA1c Retrospective statistical analysis. Results There was no significant difference in BMD of lumbar between type 2 diabetes mellitus group and non - diabetic group (control group) (P> 0.05), while BMD, FPG and HbAlc in femoral neck were significantly different (P <0.01). Conclusion The higher the FPG and HbAlc values, the lower the femoral neck BMD. Patients with poor metabolic control will result in accelerated bone loss, prone to osteoporosis.