十一个接受抗痨治疗的病人,临床和生化证明有肝脏损害。所有的病人接受利福平、异烟肼,有的还同时给予P.A.S、链梅素、乙胺丁醇和强的松。六个病人开始治疗一月内发生了肝炎,其中二人抗痨治疗前肝脏活检标本正常。一人在接受一系列抗痨药物包括P.A.S后,死于大片肝坏死。其它的病人仅是轻症肝炎。不同肝细胞嗜酸小体损害是其特点。但炎症反应很轻,局部区域和病毒性肝炎相似。临床上肝炎早期症状是明显的。所有病人,组织学检查证实肝炎早期情况不是异烟肼所 Eleven patients treated with anti-tuberculosis, clinical and biochemical evidence of liver damage. All patients received rifampin, isoniazid, and some also given P.A.S, caprin, ethambutol and prednisone. Six patients were treated for the first month of treatment with hepatitis, with two biopsies of liver biopsies normal before treatment. One died of a large necrosis of the liver after receiving a series of anti-tuberculosis drugs, including P.A.S. The other patients are only mild hepatitis. Eosinophilic damage to different hepatocytes is its characteristics. But the inflammatory response is very light, local and viral hepatitis similar. Early clinical symptoms of hepatitis are obvious. All patients, histological examination confirmed that early hepatitis is not isoniazid