以往报道了在鼠麻风杆菌(Mlm)感染的小鼠脾脏中显示有抑制性细胞.体外实验证明此细胞有多种免疫抑制功能,但在体内抗Mlm免疫反应的调节作用上,除了在麻风小鼠中对分支杆菌抗原的迟发型超敏反应(DTH)的丧失似乎相当于与脾抑制性T细胞出现的时间外,还不太清楚.因此作者设计了一系列实验对体内抑制性T细胞的作用,特 In the past, it was reported that mice showed inhibitory cells in the spleen of mice infected with M. leprae (Mlm) .In vitro experiments show that this cell has a variety of immunosuppressive functions, but in the regulation of Mlm immune response in vivo, The loss of delayed-type hypersensitivity (DTH) to mycobacterial antigens in mice appears to be equivalent to that of splenic inhibitory T cells, and the authors therefore devised a series of experiments on the inhibition of in vivo T cell inhibition Effect, special