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男,65岁,患十二指肠球部溃疡30年,常以空腹时疼痛,自服制酸,解痉药症状可以缓解。近20天疼痛加剧,无规律性,门诊对症处理,症状不能缓解。于1983年3月28日入院,入院后给予常用抗酸、解痉药疗效欠佳,尤以夜间疼痛较著,4月2日给予内服甲氰咪胍200mg每晚一次,夜间疼痛减轻。4月6日甲氰咪胍改为200mg每日4次,胃痛症状基本消失。服药后二周出现腹泻3～4次/日,开始呈糊状、后为水样便,渐增至10～14次/日,多次便检正常,
Male, 65 years old, suffering from duodenal ulcer 30 years, often fasting pain, self-service acid, antispasmodic symptoms can be alleviated. Nearly 20 days of pain intensified, irregular, out-patient symptomatic treatment, the symptoms can not be alleviated. March 28, 1983 was admitted to the hospital after admission to the common anti-acid, antispasmodic drug ineffective, especially in the nighttime pain, given on April 2 Cimetidine 200mg nightly, night pain relief. April 6 cimetidine changed 200mg 4 times a day, stomach pain symptoms disappeared. Diarrhea two or three weeks after taking medicine 3 to 4 times / day, began to paste, after the watery stools, gradually increased to 10 to 14 times / day, multiple tests were normal,