新生儿黄疸是新生儿时期最常见的表现之一,约有85%的足月儿及绝大多数早产儿在新生儿期会出现暂时性总胆红素增高[1]。非结合胆红素增高是新生儿黄疸最常见的表现形式,大多数为生理性黄疸,少数为病理性黄疸。据统计,世界上每年至少有481 000例足月儿或近足月儿患重度高胆红素血症,而其中的114 000 Neonatal jaundice is one of the most common neonatal manifestations, and about 85% of full-term infants and most preterm infants have transient total bilirubin in the neonatal period [1]. Unconjugated bilirubin is the most common neonatal jaundice manifestations, the majority of physiological jaundice, a small number of pathological jaundice. It is estimated that there are at least 481,000 full-term or near-term infants with severe hyperbilirubinemia each year in the world, of which 114,000