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[目的]探讨食管间质瘤的临床病理特征。[方法]对120例食管间叶源性肿瘤重新诊断,进行免疫组化检测,并且对食管间质瘤进行基因检测。[结果]食管间质瘤共10例,占同期间叶源性肿瘤的8.3%。食管间质瘤以吞咽困难为常见的首发症状,食管间质瘤CD117阳性率为90%,CD34阳性率为70%,SMA率阳性为40%,Desmin阳性率为20%,S100阳性率为10%。仅1例食管间质瘤病例存在c-kit基因外显子基因突变。[结论]食管间质瘤鉴别诊断需结合病理特征、免疫组化等各项指标。目前手术切除仍是其主要的治疗手段。
[Objective] To investigate the clinicopathological features of esophageal stromal tumors. [Method] A total of 120 esophageal mesenchymal tumors were re-diagnosed, detected by immunohistochemistry, and gene detection was performed on esophageal stromal tumors. [Results] A total of 10 cases of esophageal stromal tumors, accounting for 8.3% of the same period of leaf-derived tumors. Esophageal stromal tumors with dysphagia as a common first symptom, esophageal stromal tumors CD117 positive rate was 90%, CD34 positive rate was 70%, SMA rate was 40%, Desmin positive rate was 20%, S100 positive rate was 10 %. Only 1 case of esophageal stromal tumor c-kit gene exon gene mutations exist. [Conclusion] The differential diagnosis of esophageal stromal tumors should be combined with the pathological features, immunohistochemistry and other indicators. Surgical resection is still the main treatment.