肝癌显然由多病因引起,乙肝病毒和黄曲霉毒素很可能是肝癌的重要致病因素,但十多年来由于缺乏测定个体摄入水平的技术,无法开展得以最终确立病因学关系并找到有效预防途径的纵向流行病研究,故尚不能确立两者之间的因果关系。中国医学科学院肿瘤研究所孙宗棠教授领导的科研小组开展了抗黄曲霉毒素B_1M_1的高亲和力单克隆抗体以及免疫浓缩与测定技术在肝癌病因学研究中的应用研究。首先在国际上建立了较完整的具有不 Liver cancer is clearly caused by a number of causes, and hepatitis B virus and aflatoxins are likely to be important causative agents for HCC, but for more than a decade there has been a lack of technology to determine the level of individual ingestion to ultimately establish an etiological relationship and to find effective prevention Pathways of longitudinal epidemiological studies, it is still not established the causal relationship between the two. Chinese Academy of Medical Sciences Institute of Oncology led by Professor Sun Zongtang scientific research team carried out anti-aflatoxin B_1M_1 high-affinity monoclonal antibody and immunoconcentration and determination of the technology in the study of the etiology of liver cancer. First of all in the international community to establish a more complete with no