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目的观察思密达-利多卡因联合治疗青少年口腔溃疡的效果。方法 253例口腔溃疡者分为对照组及治疗组2组。对照组仅在溃疡表面涂抹思密达粉剂,治疗组先于溃疡局部涂抹盐酸利多卡因凝胶,再涂抹思密达粉剂,观察2组的疗效。结果对照组和治疗组均能促进口腔溃疡愈合(P>0.05),药物治疗3 d、5 d和7 d后,对照组疼痛的缓解率为0%、46%和94.4%,实验组为73.2%、100%和100%。结论与单用思密达组相比,思密达联合利多卡因能显著缓解青少年口腔溃疡早期的疼痛症状,但对促进溃疡愈合无明显差异。
Objective To observe the effect of combination of sida-lidocaine on oral ulcer in adolescents. Methods 253 cases of oral ulcer were divided into control group and treatment group 2 groups. The control group only smeared Smecta powder on the surface of ulcer. The treatment group first applied topical lidocaine hydrochloride gel to the ulcer and smeared Smecta powder to observe the curative effect of the two groups. Results Both the control group and the treatment group could promote the healing of oral ulcer (P> 0.05). The pain relief rates in the control group were 0%, 46% and 94.4% on the 3rd, 5th and 7th day after the drug treatment. The experimental group was 73.2 %, 100% and 100%. Conclusion Smecta combined with lidocaine can significantly relieve the early pain symptoms in young patients with oral ulcer, but there is no significant difference in promoting the healing of ulcer.