抗生素的筛选、遗传、生物合成、化学合成及作用机制等的研究正在继续取得进展,衍生物与类似物的化学合成以及分子作用机制的研究导致重要抗生素的构效关系的阐明和治疗耐药性感染与肿瘤的有效药物的发展,抗生素研究并延伸到了具有各种药理活性的低分子量酶抑制剂和免疫调节剂领域。本文综述抗生素及免疫调节剂研究的最近情况。 Research on antibiotic screening, inheritance, biosynthesis, chemical synthesis and mechanism of action are continuing to progress. The chemical synthesis of derivatives and analogues and the molecular mechanism of action have led to elucidation of the structure-activity relationship of important antibiotics and the treatment of drug resistance The development of effective drugs for infection and oncology, antibiotic research and extension to low molecular weight enzyme inhibitors and immunomodulators with various pharmacological activities. This article reviews recent developments in antibiotics and immunomodulators.