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０ 引言 热休克（ｈｅａｔｓｈｏｃｋ，ＨＳ）的研究始于１９６２年在热处理的果蝇幼虫唾液腺中发现热休克反应［１］．Ｃｕｒｒｉｅ［２］等首先研究发现经ＨＳ预处理后的大鼠离体心脏经缺血再灌注后心肌损伤较对照组减轻，心功能恢复能力增强，同时心肌内在作者简介：张
0 Introduction The study of heat shock (HS) began with the discovery of a heat shock response in the salivary glands of heat-treated Drosophila larvae in 1962 [1]. Currie [2] and other first study found that HS pretreated rat heart after myocardial ischemia-reperfusion myocardial injury than the control group to reduce cardiac function, recovery, while myocardial intrinsic