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目的：观察氯硝西泮治疗社交恐怖症的疗效。方法：社交恐怖症３６例（男性１５例，女性２１例，年龄２６ａ±ｓ８ａ，病程４．０ａ±２．０ａ）采用氯硝西泮４～１０ｍｇ／ｄ，ｐｏ，疗程８ｗｋ。另外采用丙米嗪治疗同类病人３２例（男性１４例，女性１８例，年龄２５．０ａ±２．７ａ，病程３．４ａ±２．７ａ），用量１００～３００ｍｇ／ｄ，ｐｏ，疗程８ｗｋ。结果：氯硝西泮组显效率为５６％，总有效率为８１％；丙米嗪组显效率为５０％，总有效率７５％，２组疗效差异无显著意义（Ｐ＞０．０５），氯硝西泮组不良反应较丙米嗪组少。结论：氯硝西泮对社交恐怖症有肯定的治疗作用，近、远期疗效较好，且不良反应较少。
Objective: To observe the efficacy of clonazepam in the treatment of social phobia. Methods: 36 cases of social phobia (15 males and 21 females, age 26a ± s8a, duration 4.0a ± 2.0a) were treated with clonazepam 4 ~ 10mg / d, po for 8 weeks. Another use of imipramine treatment of 32 patients (14 males, 18 females, age 25.0a ± 2.7a, duration 3.4a ± 2.7a), the amount of 100 ~ 300mg / d, po, treatment 8wk. Results: The effective rate was 56% in the clonazepam group, and the total effective rate was 81%. The effective rate was 50% and the total effective rate was 75% in the imipramine group. There was no significant difference between the two groups (P> 0.05) The side effects of clonazepam were less than that of imipramine group. Conclusion: Clonazepam has a certain therapeutic effect on social phobia. The curative effect of long-term and long-term is better with fewer adverse reactions.