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目的:评价重组人干扰素-α2b阴道泡腾胶囊与微波治疗对宫颈糜烂患者伴人乳头状瘤病毒(HPV)感染的临床疗效。方法:选择2014年2月—2016年9月间收治的宫颈糜烂伴HPV感染患者138例,将其分为治疗组和对照组,每组69例;治疗组患者给予重组人干扰素-α2b阴道泡腾胶囊与微波治疗,对照组患者则给予单用微波治疗;比较丙组患者职后的总有效率和复发率。结果:治疗后随访1年治疗组患者的总有效率为95.65%高于对照组为78.26%(P<0.05);随访6月治疗组患者的复发率为4.35%低于对照组为17.39%;1年后治疗组患者的复发率为8.70%低于对照组为30.43%(P<0.05)。结论:重组人干扰素-α2b阴道泡腾胶囊与微波治疗对宫颈糜烂伴HPV感染患者,可以有效缓解宫颈糜烂症状,且复发率较低。
Objective: To evaluate the clinical efficacy of recombinant human interferon-α 2b vaginal effervescent capsules and microwave treatment for cervical erosion patients with human papillomavirus (HPV) infection. Methods: A total of 138 cases of cervical erosion with HPV infection were selected from February 2014 to September 2016. The patients were divided into treatment group and control group, with 69 cases in each. Patients in the treatment group were given recombinant human interferon-α2b vagina Effervescent capsules and microwave treatment, while patients in the control group were treated with microwave alone. The total effective rate and recurrence rate of patients in group C were compared. Results: The total effective rate was 95.65% in the treatment group one year after treatment, 78.26% (P <0.05) in the control group. The recurrence rate in the follow - up 6 - month treatment group was 4.35%, which was 17.39% lower than that in the control group. One year later, the recurrence rate was 8.70% in the treatment group and 30.43% in the control group (P <0.05). Conclusion: Recombinant human interferon-α2b vaginal effervescent capsules and microwave treatment of cervical erosion with HPV infection in patients with cervical erosion can effectively alleviate the symptoms, and the recurrence rate is low.