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目的 探讨抗心磷脂抗体（ ＡＣＡ） 在脑梗塞中的意义及其与多项中风危险因素的关系。方法 ５８ 例急性脑梗塞患者于发病１ ～２ 天内以ＥＬＩＳＡ 方法检测血清ＡＣＡ、以ＢＭＥ１ 生物医学处理仪等分别检测血液流变学、血脂指标水平；其中２７ 例于恢复期复查血清ＡＣＡ 水平。结果 急性期ＡＣＡ１９ ．３０ ±１３ ．２７ Ｕ／ ｍｌ，恢复期ＡＣＡ１６ ．２３ ±９ ．５８ Ｕ／ ｍｌ ，两者比较无显著差异（ Ｐ＞ ０ ．０５） ，但均比对照组１０ ．４８ ±４ ．１４ Ｕ／ ｍｌ 明显增高（ Ｐ＜ ０ ．０１） ；患者血液流变学、血脂指标与对照组比较，显示有显著或非常显著差异，且患者ＡＣＡ 水平变化与血液流变学、血脂指标改变呈显著的相关关系（ ｒ ＝ ０ ．０３ ～０ ．６１ ，Ｐ＜ ０ ．０５ ～０ ．０１） 。结论 ＡＣＡ 在脑梗塞的发生中具有重要作用，且在脑梗塞的发病机制中或与多项中风危险因素共同形成了病理效应或促进了这些危险因素在脑梗塞发生中的作用，并提出了对脑梗塞患者恢复期后适当应用抗血小板药物的意义。
Objective To investigate the significance of anticardiolipin antibody (ACA) in cerebral infarction and its relationship with multiple stroke risk factors. Methods Fifty-eight patients with acute cerebral infarction were tested for serum ACA by ELISA during the first 1-2 days of onset. Blood rheology and serum lipid levels were measured by BME-1 biomedical analyzer. Among them, 27 cases were examined for ACA level . Results Acute phase of ACA19. 30 ± 13. 27 U / ml, recovery period ACA16. 23 ± 9. 58 U / ml, no significant difference between the two (P> 0.05), but both than the control group 10. 48 ± 4. 14 U / ml was significantly higher (P <0 .01); patients with hemorheology, blood lipid indicators compared with the control group showed significant or very significant difference, and ACA levels in patients with changes in hemorheology, blood lipid indicators Significant correlation (r = 0 .03 ~ 0 .61, P <0 .05 ~ 0 .01). Conclusions ACA plays an important role in the development of cerebral infarction. It also plays an important role in the pathogenesis of cerebral infarction or with multiple risk factors of stroke, and promotes the role of these risk factors in the development of cerebral infarction. Significance of Appropriate Use of Antiplatelet Drugs After Recovery in Patients with Cerebral Infarction.