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突触可塑性即突触的结构和功能发生适应性变化的能力,是指神经系统在外界环境的作用下,突触活动受到调控引起突触传递效率的易化或抑制,使得从单个神经元到整个神经环路均发生适应性变化以维持神经功能的相对稳定。其中,在中枢神经系统中(central nervous system,CNS)突触可塑性是学习与记忆的细胞分子学基础~([1])。机体可通过多种细胞分子途径调节中枢神经系统的突触可塑性,其中神经胶质细胞在突触可塑
Synaptic plasticity refers to the ability of synaptic structure and function to make adaptive changes. It refers to the facilitation or inhibition of the synaptic transmission efficiency caused by the regulation of synaptic activity under the action of the external environment by the nervous system, so that from a single neuron to The entire neural circuit undergoes adaptive changes to maintain the relative stability of neural function. Among them, synaptic plasticity in the central nervous system (CNS) is the cellular molecular basis of learning and memory ~ ([1]). The body can regulate synaptic plasticity of the central nervous system through a variety of cellular and molecular pathways, including glial cells in the synaptic plasticity