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在高原给6例低氧性肺泡通气不足、HVR减退的慢性高山病患者注射吗啡类制剂的拮抗剂纳洛酮,旨在通过纳治酮对通气的调节效应以评价内啡肽在慢性高山病发病过程中的作用。结果表明:注射前后的VE、PETCO_2、SaO_2及HVR等无明显变化。提示内啡肽未介入低氧性肺泡通气不足、慢性高山病的发病过程。
In the high altitude to six hypoxic alveolar hypoventilation, HVR decreased chronic mountain sickness patients morphine injection of antagonist naloxone, intended to regulate the effect of naturopam on ventilation to evaluate endorphins in chronic mountain sickness The role of the disease process. The results showed that VE, PETCO_2, SaO_2 and HVR did not change significantly before and after injection. Tip endorphins are not involved in hypoxic alveolar hypoventilation, the pathogenesis of chronic mountain sickness.