慢性氟中毒是地理病理学和职业病理学的结果。近年,随着氟化物在工业、农业和医学中的应用,它的重要性急剧地增加了。另外,在一些西方国家,为减少龋齿的发病率而采取的公共水源氟化使很大一部分居民长期不断地摄入氟化物。在哺乳动物中,急性大剂量氟化物中毒的症侯是包括恶心、呕吐、腹泻和痉挛在内的严重胃肠病痛,以及 Chronic fluorosis is a result of both geographic pathology and occupational pathology. In recent years, the importance of fluoride has dramatically increased with its use in industry, agriculture and medicine. In addition, in some western countries, the fluoride of public sources to reduce the incidence of dental caries has led to a long-term intake of fluoride by a large proportion of residents. In mammals, the symptoms of acute high-dose fluoride poisoning are severe gastrointestinal pain including nausea, vomiting, diarrhea and cramping, and