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近年来 ,雌激素受体 (ＥＲ)在雌激素心血管保护机制中所起作用的研究逐渐引起重视。绝经后心血管系统中ＥＲ的变化规律及意义尚未完全阐明。本研究以去势雌性大鼠模拟绝经情况 ,用受体放射配基结合分析法观察去势前后大鼠动脉壁中ＥＲ表达情况 ,并探讨其意义。一、材料、方法与
In recent years, estrogen receptor (ER) in estrogen cardiovascular protective mechanism of the role of research gradually attracted attention. The regulation and significance of ER in postmenopausal cardiovascular system have not yet been fully elucidated. In this study, the ovariectomized female rats were used to simulate the menopausal situation, and the receptor radioligand binding assay was used to observe the expression of ER in the arterial wall before and after castration, and to explore its significance. First, materials, methods and